SCHEMBL715536

SCHEMBL715536

CC(=O)Oc1cccc(CCc2ccccc2)c1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.56
LMNA P02545 1/20 0.56
NPC1 O15118 1/20 0.52
RAB9A P51151 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
ACHE P22303 5/20 0.51
PARP1 P09874 1/20 0.51
BACE1 P56817 1/20 0.50
PTGS2 P35354 1/20 0.49
ALDH1A1 P00352 2/20 0.48
KDM4E B2RXH2 1/20 0.48
PKM P14618 1/20 0.48
GAA P10253 1/20 0.48
ELANE P08246 1/20 0.47
CNR2 P34972 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL715236 0.92 LMNA (0.54) CYP3A4LMNANPC1RAB9ASMN1; SMN2
SCHEMBL10149033 0.89 SMN1; SMN2 (0.55) CYP3A4LMNANPC1RAB9ASMN1; SMN2
SCHEMBL10149053 0.89 LMNA (0.60) CYP3A4LMNAACHEPARP1ALDH1A1
SCHEMBL21225979 0.86 ALOX5 (0.57) CYP3A4LMNAACHEPARP1
SCHEMBL1561685 0.86 CYP3A4 (0.56) CYP3A4LMNAACHEPARP1PTGS2
SCHEMBL27348013 0.85 ACHE (0.70) CYP3A4LMNAACHEPARP1
SCHEMBL7613234 0.85 CYP3A4 (0.54) CYP3A4LMNAACHEPARP1CNR2
SCHEMBL13314605 0.85 ALDH1A1 (0.55) CYP3A4LMNANPC1RAB9ASMN1; SMN2
SCHEMBL717987 0.84 NPC1 (0.65) LMNANPC1RAB9ASMN1; SMN2BACE1
SCHEMBL717746 0.83 GABRA1 (0.54) CYP3A4NPC1RAB9ASMN1; SMN2BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200188878-A1 MOLECULARLY IMPRINTED POLYMERS MONASH UNIVERSITY (AU) 2020-06-18 US disclosed
US-20200188878-A1 MOLECULARLY IMPRINTED POLYMERS MONASH UNIVERSITY (AU) 2020-06-18 US disclosed
US-20160288090-A1 MOLECULARLY IMPRINTED POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2016-10-06 US disclosed
US-20160288090-A1 MOLECULARLY IMPRINTED POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2016-10-06 US disclosed
US-20160288090-A1 MOLECULARLY IMPRINTED POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2016-10-06 US disclosed
US-20120052757-A1 MOLECULARLY IMPRINTED POLYMERS MONASH UNIVERSITY (AU) 2012-03-01 US disclosed
US-20120052757-A1 MOLECULARLY IMPRINTED POLYMERS MONASH UNIVERSITY (AU) 2012-03-01 US disclosed
US-20120052757-A1 MOLECULARLY IMPRINTED POLYMERS MONASH UNIVERSITY (AU) 2012-03-01 US disclosed
EP-2391658-A1 MOLECULARLY IMPRINTED POLYMERS Commonwealth Scientific and Industrial Research Organisation (AU) 2011-12-07 EP disclosed
WO-2010085851-A1 MOLECULARLY IMPRINTED POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2010-08-05 WO disclosed
EP-0306411-A2 Ethanone oximes MITSUBISHI KASEI CORPORATION (JP) 1989-03-08 EP disclosed
US-4579677-A CONTAINING PHENOLIC COMPOUND, OIL, CARBONYL COMPOUND, POLYCYCLIC COMPOUND, ESTER, AND ALCOHOL LEVER BROTHERS COMPANY (US) 1986-04-01 US disclosed
US-4469848-A POLISHES FOR FLOORS, FURNITURE AND WINDOWS LEVER BROTHERS COMPANY (US) 1984-09-04 US disclosed
US-4347153-A PHENOL; ALDEHYDE OR KETONE; ESTER; ALCOHOL; POLYCYCLIC COMPOUND; VEGETABLE OR SYNTHETIC OIL, EXTRACT, RESIN LEVER BROTHERS COMPANY (US) 1982-08-31 US disclosed
US-4343783-A FOR DEODORIZING SKIN OR HAIR LEVER BROTHERS COMPANY (US) 1982-08-10 US disclosed
US-4322308-A Detergent product containing deodorant compositions LEVER BROTHERS COMPANY (US) 1982-03-30 US disclosed
US-4304679-A NON-SOAP DETERGENTS LEVER BROTHERS COMPANY (US) 1981-12-08 US disclosed
US-4289641-A FOR LAUNDERING FABRICS SUBSEQUENTLY WORN IN CONTACT OF SKIN AND SWEAT GLANDS, DEODORIZING LEVER BROTHERS COMPANY (US) 1981-09-15 US disclosed
US-4288341-A SOAP CONTAINING LIBOXIDASE INHIBITOR LEVER BROTHERS COMPANY (US) 1981-09-08 US disclosed
US-4278658-A PHENOLIC COMPOUNDS, OILS, ALDEHYDES, KETONES LEVER BROTHERS COMPANY (US) 1981-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160288090-A1 MOLECULARLY IMPRINTED POLYMERS IPMK, MPI, PIM3 CYP3A4 780/4885LMNA 3479/4885NPC1 3562/4885
US-20120052757-A1 MOLECULARLY IMPRINTED POLYMERS IPMK, MPI, PIM3 CYP3A4 780/4885LMNA 3479/4885NPC1 3562/4885
US-20200188878-A1 MOLECULARLY IMPRINTED POLYMERS IPMK, MPI, PIM3 CYP3A4 780/4885LMNA 3479/4885NPC1 3562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.