SCHEMBL27351237

SCHEMBL27351237

CCCCCCCCCCCCCCON(c1ccccc1)c1ccc(NC(=O)c2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
PPARA Q07869 1/20 0.53
GPR35 Q9HC97 1/20 0.53
SMN1; SMN2 Q16637 3/20 0.52
RAB9A P51151 3/20 0.52
NPC1 O15118 2/20 0.52
GAA P10253 1/20 0.52
NR1H4 Q96RI1 3/20 0.50
TRPV1 Q8NER1 1/20 0.49
ALDH1A1 P00352 3/20 0.48
MAPT P10636 2/20 0.48
TSHR P16473 2/20 0.48
NPSR1 Q6W5P4 1/20 0.48
HDAC3 O15379 1/20 0.48
HDAC1 Q13547 1/20 0.48
HDAC2 Q92769 1/20 0.48
NCOR2 Q9Y618 1/20 0.48
FAAH O00519 6/20 0.47
KDM4E B2RXH2 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27362586 0.95 TRPV1 (0.55) MEN1KMT2APPARAGPR35SMN1; SMN2
SCHEMBL27452702 0.88 NAAA (0.49) MEN1KMT2ASMN1; SMN2RAB9ANPC1
SCHEMBL27360513 0.83 HDAC3 (0.58) HDAC3HDAC1HDAC2NAAA
SCHEMBL27379185 0.82 L3MBTL1 (0.54) MEN1KMT2ASMN1; SMN2RAB9ANPC1
SCHEMBL27362584 0.82 TP53 (0.57) RAB9ANPC1MAPTTSHR
SCHEMBL9453351 0.81 NR1H4 (0.73) MEN1KMT2ASMN1; SMN2RAB9ANPC1
SCHEMBL27376842 0.81 ALDH1A1 (0.47) SMN1; SMN2RAB9ANPC1ALDH1A1MAPT
SCHEMBL28194680 0.80 ALDH1A1 (0.47) SMN1; SMN2RAB9ANPC1ALDH1A1MAPT
SCHEMBL27361074 0.80 ALDH1A1 (0.47) SMN1; SMN2RAB9ANPC1ALDH1A1MAPT
SCHEMBL27382622 0.80 ALDH1A1 (0.49) MEN1KMT2ASMN1; SMN2RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1056494-A The bis-aryl amide of platelet activating factor and urea antagonists AMERICAN CYANAMID CO (US) 1991-11-27 CN disclosed