Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 7/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.56 |
| ▸ | NAAA | Q02083 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27452702 | 0.85 | NAAA (0.49) | NAAA | |
| SCHEMBL27351237 | 0.83 | MEN1 (0.53) | HDAC3HDAC1HDAC2NAAA | |
| SCHEMBL9307359 | 0.82 | SMN1; SMN2 (0.67) | HDAC3HDAC1HDAC2NAAA | |
| SCHEMBL27362586 | 0.81 | TRPV1 (0.55) | — | |
| SCHEMBL27379185 | 0.80 | L3MBTL1 (0.54) | — | |
| SCHEMBL27362584 | 0.80 | TP53 (0.57) | — | |
| SCHEMBL27379186 | 0.79 | ALDH1A1 (0.44) | — | |
| SCHEMBL27362585 | 0.79 | MEN1 (0.42) | — | |
| SCHEMBL27376842 | 0.79 | ALDH1A1 (0.47) | — | |
| SCHEMBL27361074 | 0.78 | ALDH1A1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1069025-A | The aryl of platelet activating factor, acid amides, imide and carbamate pyridine antagonists | AMERICAN CYANAMID CO (US) | 1993-02-17 | — | — | CN | disclosed |