Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.35 |
| ▸ | RXRB | P28702 | 2/20 | 0.35 |
| ▸ | RXRG | P48443 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30995622 | 1.00 | RXRA (0.35) | RXRARXRBRXRGALDH1A1HTT | |
| SCHEMBL30995659 | 0.91 | L3MBTL1 (0.31) | KDM4ENPSR1ADRB2ADRB1ADRA2A | |
| SCHEMBL27353054 | 0.91 | L3MBTL1 (0.31) | KDM4ENPSR1ADRB2ADRB1ADRA2A | |
| SCHEMBL27353040 | 0.90 | ALDH1A1 (0.33) | ALDH1A1HTTKDM4ENPSR1ADRB2 | |
| SCHEMBL27352983 | 0.83 | CTSS (0.33) | — | |
| SCHEMBL30995619 | 0.83 | CTSS (0.33) | — | |
| SCHEMBL27352992 | 0.83 | CTSS (0.33) | — | |
| SCHEMBL27353173 | 0.82 | ALDH1A1 (0.39) | RXRARXRBRXRGALDH1A1HTT | |
| SCHEMBL30995621 | 0.80 | SCN9A (0.33) | RXRARXRBRXRGALDH1A1KDM4E | |
| SCHEMBL27353159 | 0.80 | SCN9A (0.33) | RXRARXRBRXRGALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024126650-A1 | NOVEL BICYCLIC-CARBOXAMIDE COMPOUNDS USEFUL AS PESTICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2024-06-20 | — | — | WO | disclosed |