Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 4/20 | 0.37 |
| ▸ | RXRB | P28702 | 3/20 | 0.37 |
| ▸ | RXRG | P48443 | 3/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27353177 | 0.83 | AAK1 (0.41) | ALDH1A1HTTRXRARXRBRXRG | |
| SCHEMBL30995622 | 0.82 | RXRA (0.35) | ALDH1A1HTTRXRARXRBRXRG | |
| SCHEMBL27353047 | 0.82 | RXRA (0.35) | ALDH1A1HTTRXRARXRBRXRG | |
| SCHEMBL27353032 | 0.72 | ACHE (0.41) | ALDH1A1ADRB2ADRB1KDM4EADRB3 | |
| SCHEMBL27353039 | 0.72 | ACHE (0.41) | ALDH1A1ADRB2ADRB1KDM4EADRB3 | |
| SCHEMBL30995609 | 0.72 | ALDH1A1 (0.42) | ALDH1A1ADRB2ADRB1KDM4EADRB3 | |
| SCHEMBL30995659 | 0.72 | L3MBTL1 (0.31) | ADRB2ADRB1KDM4ETP53ADRA2A | |
| SCHEMBL27353026 | 0.72 | ALDH1A1 (0.42) | ALDH1A1ADRB2ADRB1KDM4EADRB3 | |
| SCHEMBL27353054 | 0.72 | L3MBTL1 (0.31) | ADRB2ADRB1KDM4ETP53ADRA2A | |
| SCHEMBL27353040 | 0.72 | ALDH1A1 (0.33) | ALDH1A1HTTADRB2ADRB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024126650-A1 | NOVEL BICYCLIC-CARBOXAMIDE COMPOUNDS USEFUL AS PESTICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2024-06-20 | — | — | WO | disclosed |