Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 7/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770958 | 0.80 | REN (0.43) | RENMETAP2METAP1CTSLCTSB | |
| SCHEMBL9831712 | 0.79 | REN (0.42) | RENMETAP2METAP1CTSLCTSB | |
| SCHEMBL7037201 | 0.78 | REN (0.44) | RENCTSLCTSBCTSSCTSK | |
| SCHEMBL7037199 | 0.78 | REN (0.44) | RENCTSLCTSBCTSSCTSK | |
| SCHEMBL15619034 | 0.77 | CYP3A4 (0.44) | RENCTSLCTSBCTSSCTSK | |
| SCHEMBL15619033 | 0.77 | CYP3A4 (0.44) | RENCTSLCTSBCTSSCTSK | |
| SCHEMBL8759874 | 0.75 | METAP2 (0.47) | METAP2METAP1CTSLCTSBCTSS | |
| SCHEMBL10521193 | 0.74 | CTSL (0.49) | RENMETAP2METAP1CTSLCTSB | |
| SCHEMBL9515866 | 0.74 | REN (0.53) | RENCTSL | |
| SCHEMBL9515874 | 0.74 | REN (0.53) | RENCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1027271-C | Preparation method of n-statinib and n-cyclostatini polypeptide | PFICER CO LTD (US) | 1995-01-04 | — | — | CN | disclosed |
| CN-87101499-A | Preparation method of n-statinib and n-cyclostatini polypeptide | — | 1988-05-11 | — | — | CN | disclosed |