Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 5/20 | 0.43 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831712 | 0.84 | REN (0.42) | RENHTRA1CTSLCTSBCTSS | |
| SCHEMBL27353143 | 0.80 | REN (0.44) | RENHTRA1CTSLCTSBCTSS | |
| SCHEMBL7037201 | 0.80 | REN (0.44) | RENCTSLCTSBCTSSCTSK | |
| SCHEMBL7037199 | 0.80 | REN (0.44) | RENCTSLCTSBCTSSCTSK | |
| SCHEMBL15619034 | 0.79 | CYP3A4 (0.44) | RENCTSLCTSBCTSSCTSK | |
| SCHEMBL15619033 | 0.79 | CYP3A4 (0.44) | RENCTSLCTSBCTSSCTSK | |
| SCHEMBL7207431 | 0.76 | CTSL (0.40) | CTSLCTSBCTSSCTSKCYP3A4 | |
| SCHEMBL7437518 | 0.75 | CTSB (0.40) | RENCTSLCTSBCTSSCTSK | |
| SCHEMBL11020489 | 0.75 | REN (0.43) | RENHTRA1CTSLCTSBCTSS | |
| SCHEMBL7294934 | 0.74 | CYP3A4 (0.43) | RENCTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045537-A | Treating Diseases Caused by Retroviruses | SANDOZ LTD. (CH) | 1991-09-03 | — | — | US | disclosed |