Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5315560 | 0.84 | CA2 (0.47) | CA2 | |
| SCHEMBL22118297 | 0.72 | PIK3CA (0.41) | CA2CA1 | |
| SCHEMBL22118298 | 0.72 | PIK3CA (0.41) | CA2CA1 | |
| SCHEMBL449446 | 0.72 | MAOA (0.34) | ATMNISCHCYP2C9 | |
| SCHEMBL7347250 | 0.72 | KDM1A (0.35) | ATMNISCHCYP2C9 | |
| SCHEMBL1519101 | 0.70 | ALDH1A1 (0.39) | ATMPOLBCYP2C9 | |
| SCHEMBL10672022 | 0.69 | CA2 (0.37) | CA2ATMCA1CYP2C9 | |
| SCHEMBL6992306 | 0.69 | HTR6 (0.39) | CA2CA1 | |
| SCHEMBL17185573 | 0.68 | MAOA (0.34) | NISCH | |
| SCHEMBL28596155 | 0.68 | MAOA (0.34) | NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1244575-C | Sulfonylalkylamido hydroxyethylamino sulfonamide retroviral protease inhibitors | SEARLE & CO (US) | 2006-03-08 | — | — | CN | disclosed |
| CN-1050839-C | Novel sulfonylamino pyrimidines | HOFFMANN LA ROCHE (CH) | 2000-03-29 | — | — | CN | disclosed |
| CN-1183767-A | Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors | SEARLE & CO (US) | 1998-06-03 | — | — | CN | disclosed |
| CN-1106007-A | Novel sulfonylamino pyrimidines | HOFFMANN LA ROCHE (CH) | 1995-08-02 | — | — | CN | disclosed |