SCHEMBL27353306

SCHEMBL27353306

Clc1cc(-c2ccccc2)cc(-c2cc(C3=CCCC=C3)cc(-c3ccccc3)c2)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.36
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35
RXRA P19793 2/20 0.33
RXRB P28702 2/20 0.33
PTPN1 P18031 1/20 0.31
DUSP3 P51452 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.30
ALDH1A1 P00352 2/20 0.30
KDM4E B2RXH2 1/20 0.30
POLB P06746 1/20 0.30
HTT P42858 1/20 0.30
ADORA2A P29274 1/20 0.30
ADORA2B P29275 1/20 0.30
ADORA1 P30542 1/20 0.30
NPC1 O15118 1/20 0.30
TP53 P04637 1/20 0.30
TSHR P16473 1/20 0.30
NFKB1 P19838 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24330955 0.86 MEN1 (0.35) CYP1A2RXRARXRBALDH1A1KDM4E
SCHEMBL26326993 0.85 GLO1 (0.32) ALDH1A1
SCHEMBL25692683 0.83 ALDH1A1 (0.36) SLC6A2SLC6A4SMN1; SMN2ALDH1A1NPC1
SCHEMBL13523401 0.83 ALDH1A1 (0.30) ALDH1A1
SCHEMBL13816479 0.83 MAOA (0.41) ALDH1A1KDM4EHTT
SCHEMBL23783891 0.82 MAOA (0.38) ALDH1A1KDM4EHTTNPC1
SCHEMBL17726107 0.80 ALDH1A1 (0.39) CYP1A2SMN1; SMN2ALDH1A1NPC1NFKB1
SCHEMBL3807753 0.80 ALDH1A1 (0.36) SMN1; SMN2ALDH1A1NPC1NFKB1RAB9A
SCHEMBL17643182 0.80 TRIM24 (0.36) ALDH1A1KDM4EPOLBNPC1TP53
SCHEMBL26151111 0.80 RXRA (0.35) RXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024014866-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 솔루스첨단소재 주식회사 2024-01-18 WO disclosed