SCHEMBL17643182

SCHEMBL17643182

O=Cc1cc(C2=CCCC=C2)cc(-c2ccccc2)c1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 1/20 0.36
TRIM33 Q9UPN9 1/20 0.36
ALDH1A1 P00352 2/20 0.34
CYP2A6 P11509 1/20 0.34
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
IP6K1 Q92551 1/20 0.31
AXL P30530 1/20 0.31
TP53 P04637 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
POLB P06746 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26326993 0.81 GLO1 (0.32) ALDH1A1
SCHEMBL17726107 0.80 ALDH1A1 (0.39) ALDH1A1CA1CA2MEN1NPC1
SCHEMBL3807753 0.80 ALDH1A1 (0.36) ALDH1A1NPC1
SCHEMBL25692683 0.80 ALDH1A1 (0.36) ALDH1A1TP53NPC1
SCHEMBL13816479 0.80 MAOA (0.41) ALDH1A1KDM4EMEN1KMT2A
SCHEMBL13523401 0.80 ALDH1A1 (0.30) ALDH1A1
SCHEMBL27353306 0.80 CYP1A2 (0.36) ALDH1A1TP53KDM4ENPC1POLB
SCHEMBL23783891 0.79 MAOA (0.38) ALDH1A1KDM4EMEN1NPC1KMT2A
SCHEMBL7902633 0.78 ALDH1A1 (0.55) TRIM24TRIM33ALDH1A1CYP2A6CA12
SCHEMBL26151111 0.76 RXRA (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016045765-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2016-03-31 WO disclosed