Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6754441 | 0.79 | NR1H3 (0.53) | — | |
| SCHEMBL4139801 | 0.79 | KDM4E (0.60) | KDM4EALDH1A1ROCK1ROCK2EPHX2 | |
| SCHEMBL14987027 | 0.79 | KDM4E (0.62) | KDM4EALDH1A1ROCK1ROCK2EPHX2 | |
| SCHEMBL13357674 | 0.78 | ROCK1 (0.56) | ROCK1CYP3A4ITGB3ITGA2B | |
| SCHEMBL19920047 | 0.76 | GLS (0.55) | ITGB3ITGA2B | |
| SCHEMBL5752269 | 0.75 | LTA4H (0.64) | ALDH1A1HRH3 | |
| SCHEMBL13865084 | 0.75 | ALDH1A1 (0.51) | KDM4EALDH1A1ROCK1ROCK2EPHX2 | |
| SCHEMBL11209971 | 0.74 | PLA2G4B (0.61) | — | |
| SCHEMBL7401219 | 0.74 | TMEM97 (0.68) | KDM4EALDH1A1 | |
| SCHEMBL22266155 | 0.74 | LTA4H (0.62) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006742-A2 | NRF2 PROTEIN DEGRADERS | DRACEN PHARMACEUTICALS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |