Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | AKT2 | P31751 | 2/20 | 0.32 |
| ▸ | QPCT | Q16769 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6527231 | 0.80 | TAAR1 (0.47) | ADRA2AADRA1DADRA1AADRA1BLMNA | |
| SCHEMBL27342986 | 0.79 | LMNA (0.37) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL27343501 | 0.72 | ACP3 (0.40) | MEN1RAB9AKMT2A | |
| SCHEMBL4682376 | 0.70 | ALDH1A1 (0.32) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL4682380 | 0.70 | FDPS (0.33) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL8712604 | 0.70 | TAAR1 (0.61) | ADRA2AADRA2BADRA2CADRA1DHTR1D | |
| SCHEMBL12854154 | 0.70 | — | — | |
| SCHEMBL9692794 | 0.70 | HDAC6 (0.34) | ADRA2AADRA2BADRA2CADRA1DHTR1D | |
| SCHEMBL27357182 | 0.70 | CDK8 (0.37) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL27341816 | 0.70 | FGFR1 (0.43) | HTR1BQPCTLMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1058594-A | Imidazo [4,5-C] pyridines osteoporosis agent | AMERICAN HOME PROD (US) | 1992-02-12 | — | — | CN | claimed |
| CN-1058594-A | Imidazo [4,5-C] pyridines osteoporosis agent | AMERICAN HOME PROD (US) | 1992-02-12 | — | — | CN | disclosed |