SCHEMBL2735754

SCHEMBL2735754

C=CCOP(=O)(OCC=C)c1ccc(-c2ccc(P(=O)(OCC=C)OCC=C)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CYP3A4 P08684 1/20 0.32
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
LIG1 P18858 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL331731 0.84 PKM (0.49) PKMSMN1; SMN2CYP3A4ALOX15TSHR
Vinyl Chloride SCHEMBL11613404 0.79 PKM (0.45) PKMSMN1; SMN2CYP3A4ALOX15TSHR
SCHEMBL6545061 0.79 MAPT (0.49) SMN1; SMN2TSHRALDH1A1TDP1CA12
SCHEMBL6545599 0.78 MAOA (0.38) SMN1; SMN2CYP3A4TSHRALDH1A1CA2
SCHEMBL11312456 0.77 MEN1 (0.48) PKMSMN1; SMN2ALOX15TSHRALDH1A1
SCHEMBL6545932 0.76 LMNA (0.43) SMN1; SMN2TSHRALDH1A1CA12CA1
SCHEMBL11325269 0.74 PKM (0.44) PKMSMN1; SMN2CYP3A4ALOX15TSHR
SCHEMBL11312190 0.73 ALDH1A1 (0.41) PKMSMN1; SMN2CYP3A4ALOX15TSHR
SCHEMBL3664162 0.73 MAOB (0.34) ALDH1A1
SCHEMBL8741331 0.73 L3MBTL1 (0.61) PKMSMN1; SMN2ALOX15TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8115134-B2 Arc extinguishing resin processed article and circuit breaker using the same FUJI ELECTRIC FA COMPONENTS & SYSTEMS CO., LTD. (JP) 2012-02-14 US disclosed
US-8089023-B2 Arc-extinguishing processed resin article and circuit breaker that uses same FUJI ELECTRIC FA COMPONENTS & SYSTEMS CO., LTD. 2012-01-03 US disclosed
US-20090283500-A1 ARC EXTINGUISHING RESIN PROCESSED ARTICLE AND CIRCUIT BREAKER USING THE SAME FUJI ELECTRIC FA COMPONENTS & SYSTEMS CO., LTD. (JP) 2009-11-19 US disclosed
US-20090200272-A1 ARC-EXTINGUISHING PROCESSED RESIN ARTICLE AND CIRCUIT BREAKER THAT USES SAME FUJI ELECTRIC FA COMPONENTS & SYSTEMS CO., LTD. (JP) 2009-08-13 US disclosed