Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18932521 | 0.72 | CA2 (0.39) | ALDH1A1GABRA1GABRB2 | |
| SCHEMBL6305769 | 0.70 | CA2 (0.38) | KDM4EALDH1A1CYP1A2MAPTALOX15 | |
| SCHEMBL10389578 | 0.68 | ALDH1A1 (0.36) | KDM4EALDH1A1CYP1A2MAPTALOX15 | |
| SCHEMBL28633093 | 0.66 | GABRA1 (0.36) | KDM4EALDH1A1CYP1A2MAPTALOX15 | |
| SCHEMBL13280565 | 0.65 | GABRA1 (0.43) | KDM4EALDH1A1CYP1A2MAPTALOX15 | |
| SCHEMBL12105910 | 0.64 | ALDH1A1 (0.40) | ALDH1A1CYP1A2MAPTALOX15SMN1; SMN2 | |
| SCHEMBL17591344 | 0.64 | — | — | |
| SCHEMBL15627018 | 0.64 | ALDH1A1 (0.36) | KDM4EALDH1A1CYP1A2MAPTALOX15 | |
| SCHEMBL29822860 | 0.64 | GABBR2 (0.36) | KDM4EALDH1A1CYP1A2MAPTALOX15 | |
| SCHEMBL10388767 | 0.63 | ALDH1A1 (0.50) | KDM4EALDH1A1CYP1A2MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1073563-C | 4, 6-di-tert-butyl-2, 3-dihydrobenzothiophene derivatives | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2001-10-24 | — | — | CN | disclosed |
| CN-1148386-A | 4,6-di-5-butyl-2,3-dihydrobenzothiophene derivative | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1997-04-23 | — | — | CN | disclosed |