Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18472040 | 0.82 | POLB (0.34) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL3744381 | 0.82 | POLB (0.34) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL21026696 | 0.82 | POLB (0.34) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL27358272 | 0.81 | PDE4A (0.33) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL18009175 | 0.77 | KEAP1 (0.30) | — | |
| SCHEMBL31441632 | 0.76 | ITGB1 (0.32) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL792893 | 0.76 | ITGB1 (0.32) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL18009316 | 0.75 | NFE2L2 (0.43) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL18009315 | 0.75 | NFE2L2 (0.43) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL18009313 | 0.75 | NFE2L2 (0.43) | PDE4APDE4BPDE4CPDE4DTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130344-A1 | TRANSIENT RECEPTOR POTENTIAL VANILLOID 6 INHIBITORS | UNIQUEST PTY LIMITED (AU) | 2024-06-27 | — | — | WO | disclosed |