Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.32 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.32 |
| ▸ | ITGAL | P20701 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 3/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31441632 | 1.00 | ITGB1 (0.32) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL21026696 | 0.82 | POLB (0.34) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL18725504 | 0.82 | ATM (0.36) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3744381 | 0.82 | POLB (0.34) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL18472040 | 0.82 | POLB (0.34) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL18009175 | 0.80 | KEAP1 (0.30) | — | |
| SCHEMBL12414703 | 0.77 | TSHR (0.36) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL12414701 | 0.77 | TSHR (0.36) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL27358271 | 0.76 | PDE4A (0.35) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL27358272 | 0.76 | PDE4A (0.33) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2615911-A1 | PESTICIDE PREPARATIONS CONTAINING N-SUBSTITUTED 2-PYRROLIDONE-4-CARBONIC ACID ESTERS | Clariant Finance (BVI) Limited (VG) | 2013-07-24 | — | — | EP | claimed |
| EP-2616438-A1 | USE OF N-SUBSTITUTED 2-PYRROLIDONE-4-CARBONIC ACID ESTERS AS SOLVENTS | Clariant Finance (BV) Limited (VG) | 2013-07-24 | — | — | EP | claimed |
| EP-2480071-A1 | PESTICIDE PREPARATIONS CONTAINING DERIVATIVES OF PYRROLIDONE-4-CARBOXYLIC ACID | Clariant Finance (BVI) Limited (VG) | 2012-08-01 | — | — | EP | claimed |
| WO-2012034689-A1 | PESTICIDE PREPARATIONS CONTAINING N-SUBSTITUTED 2-PYRROLIDONE-4-CARBONIC ACID ESTERS | CLARIANT INTERNATIONAL LTD (CH) | 2012-03-22 | — | — | WO | claimed |
| WO-2012034688-A1 | USE OF N-SUBSTITUTED 2-PYRROLIDONE-4-CARBONIC ACID ESTERS AS SOLVENTS | CLARIANT INTERNATIONAL LTD (CH) | 2012-03-22 | — | — | WO | claimed |
| WO-2011035873-A1 | PESTICIDE PREPARATIONS CONTAINING DERIVATIVES OF PYRROLIDONE-4-CARBOXYLIC ACID | CLARIANT INTERNATIONAL LTD (CH) | 2011-03-31 | — | — | WO | claimed |
| WO-2004056885-A1 | POLYMER-CONTAINING PYRROLIDONE-4-CARBOXYLIC ACID GROUPS AND THE USE THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2004-07-08 | — | — | WO | claimed |
| EP-0132811-A1 | 1-Substituted 4-hydroxymethyl-pyrrolidinones, processes for their preparation, pharmaceutical composition and intermediate | BOEHRINGER INGELHEIM KG (DE) | 1985-02-13 | — | — | EP | claimed |
| US-20250270222-A1 | AP2 ASSOCIATED KINASE 1 INHIBITORS AND USES THEREOF | SATELLOS BIOSCIENCE INC. (CA) | 2025-08-28 | — | — | US | disclosed |
| US-20250122207-A1 | AP2 ASSOCIATED KINASE 1 INHIBITORS AND USES THEREOF | SATELLOS BIOSCIENCE INC. (CA) | 2025-04-17 | — | — | US | disclosed |
| WO-2025054448-A1 | AP2 ASSOCIATED KINASE 1 INHIBITORS AND USES THEREOF | SATELLOS BIOSCIENCE INC. (CA) | 2025-03-13 | — | — | WO | disclosed |
| EP-2301520-B1 | Oxidative dye | HENKEL AG & CO KGAA (DE) | 2017-03-08 | — | — | EP | disclosed |
| WO-2014037109-A1 | METHOD FOR PRODUCING N-SUBSTITUTED PYRROLIDONECARBOXYLIC ESTERS | CLARIANT INTERNATIONAL LTD (CH) | 2014-03-13 | — | — | WO | disclosed |
| WO-2014037109-A1 | METHOD FOR PRODUCING N-SUBSTITUTED PYRROLIDONECARBOXYLIC ESTERS | CLARIANT INTERNATIONAL LTD (CH) | 2014-03-13 | — | — | WO | disclosed |
| EP-1575925-A1 | NOVEL CARBOXAMIDES, THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004056784-A1 | NOVEL CARBOXAMIDES, THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-07-08 | — | — | WO | disclosed |
| EP-0601321-B1 | Binders composition for electrodeposition | BASF LACKE & FARBEN (DE) | 1997-02-19 | — | — | EP | disclosed |
| EP-0601321-A1 | Binders composition for electrodeposition | BASF Lacke + Farben AG (DE) | 1994-06-15 | — | — | EP | disclosed |
| EP-0132811-B1 | 1-SUBSTITUTED 4-HYDROXYMETHYL-PYRROLIDINONES, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITION AND INTERMEDIATE | BOEHRINGER INGELHEIM KG (DE) | 1988-09-28 | — | — | EP | disclosed |
| EP-0132811-A1 | 1-Substituted 4-hydroxymethyl-pyrrolidinones, processes for their preparation, pharmaceutical composition and intermediate | BOEHRINGER INGELHEIM KG (DE) | 1985-02-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250122207-A1 | AP2 ASSOCIATED KINASE 1 INHIBITORS AND USES THEREOF | AAK1, CAMKK1, AP2A1 | ITGB1 2365/4885ITGA5 3951/4885ITGB3 3012/4885 |
| US-20250270222-A1 | AP2 ASSOCIATED KINASE 1 INHIBITORS AND USES THEREOF | AAK1, AP2A1, CSNK1A1 | ITGB1 2209/4885ITGA5 4179/4885ITGB3 2874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.