Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | FLT1 | P17948 | 4/20 | 0.41 |
| ▸ | FLT4 | P35916 | 4/20 | 0.41 |
| ▸ | KDR | P35968 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27548588 | 0.91 | ALDH1A1 (0.44) | KIF18AKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL27375130 | 0.89 | KIF18A (0.48) | KIF18AKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL27355044 | 0.89 | MAPT (0.49) | KIF18AKMT2AMEN1FLT1FLT4 | |
| SCHEMBL27373709 | 0.88 | KMT2A (0.42) | KIF18AKMT2AMEN1FLT1FLT4 | |
| SCHEMBL6935453 | 0.86 | SLC9A1 (0.50) | KIF18A | |
| SCHEMBL27466628 | 0.86 | KIF18A (0.45) | KIF18AKMT2AMEN1FLT1FLT4 | |
| SCHEMBL27467070 | 0.84 | ABCC9 (0.39) | KIF18AKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL27353903 | 0.84 | LMNA (0.49) | KIF18AKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL27447157 | 0.81 | POLB (0.40) | KMT2AMEN1ALDH1A1POLBHTT | |
| SCHEMBL27374122 | 0.81 | SLC9A1 (0.47) | POLBHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1071743-C | Sulfuryl or sulfinyl benzoyl guanidine derivative | MERCK PATENT GMBH (DE) | 2001-09-26 | — | — | CN | disclosed |
| CN-1148590-A | Sulfuryl or sulfinyl benzoyl guanidine derivative | MERCK PATENT GMBH (DE) | 1997-04-30 | — | — | CN | disclosed |