Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.59 |
| ▸ | CTSS | P25774 | 5/20 | 0.59 |
| ▸ | CTSB | P07858 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | PREP | P48147 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2864243 | 0.81 | CTSL (0.49) | CTSLCTSSCTSBALDH1A1CTSK | |
| SCHEMBL9900827 | 0.80 | CTSL (0.63) | CTSLCTSSCTSBALDH1A1CTSK | |
| SCHEMBL4861409 | 0.80 | CTSL (0.53) | CTSLCTSSCTSBALDH1A1LMNA | |
| SCHEMBL3647693 | 0.80 | CTSL (0.53) | CTSLCTSSCTSBALDH1A1LMNA | |
| SCHEMBL25857104 | 0.80 | CTSL (0.53) | CTSLCTSSCTSBALDH1A1LMNA | |
| SCHEMBL6381245 | 0.78 | CPB1 (0.56) | CTSLCTSSCTSBALDH1A1CTSK | |
| SCHEMBL4549855 | 0.78 | LMNA (0.54) | CTSLCTSSCTSBALDH1A1LMNA | |
| SCHEMBL16590476 | 0.78 | FKBP1A (0.60) | CTSLCTSSCTSBALDH1A1CTSK | |
| SCHEMBL4870701 | 0.78 | LMNA (0.54) | CTSLCTSSCTSBALDH1A1LMNA | |
| SCHEMBL1745955 | 0.77 | HTT (0.51) | CTSLCTSSCTSBALDH1A1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1066712-C | Prolinamide derivatives | MITSUBISHI CHEM CORP (JP) | 2001-06-06 | — | — | CN | disclosed |