Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | HCK | P08631 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31194316 | 0.87 | MET (0.43) | METGABRG2GABRB3GABRA5KDM4E | |
| SCHEMBL25229548 | 0.82 | ALDH1A1 (0.41) | METMAPTBRD4GABRG2GABRB3 | |
| SCHEMBL20483115 | 0.81 | KDM4E (0.39) | METGABRG2GABRB3GABRA5KDM4E | |
| SCHEMBL25909811 | 0.81 | HSP90AA1 (0.41) | METBRD4GABRG2GABRB3GABRA5 | |
| SCHEMBL31194282 | 0.79 | GABRG2 (0.39) | METGABRG2GABRB3GABRA5KDM4E | |
| SCHEMBL29632068 | 0.78 | KDM4E (0.48) | MAPTBRD4JMJD6KDM4EALDH1A1 | |
| SCHEMBL1623467 | 0.78 | KDM4E (0.48) | MAPTBRD4JMJD6KDM4EALDH1A1 | |
| SCHEMBL19707129 | 0.77 | MET (0.39) | METGABRG2GABRB3GABRA5KDM4E | |
| SCHEMBL29650289 | 0.77 | MET (0.39) | METGABRG2GABRB3GABRA5KDM4E | |
| SCHEMBL30066410 | 0.75 | PIK3CD (0.44) | MAPTRAB9ABRD4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024035950-A1 | INHIBITORS OF KIF18A AND USES THEREOF | ACCENT THERAPEUTICS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |
| WO-2024035950-A1 | INHIBITORS OF KIF18A AND USES THEREOF | ACCENT THERAPEUTICS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |