Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | BUB1 | O43683 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | HCK | P08631 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.36 |
| ▸ | PRKDC | P78527 | 2/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.36 |
| ▸ | MET | P08581 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20483115 | 0.82 | KDM4E (0.39) | GABRG2GABRB3GABRA5BUB1KDM4E | |
| SCHEMBL25909811 | 0.82 | HSP90AA1 (0.41) | GABRG2GABRB3GABRA5BUB1KDM4E | |
| SCHEMBL25229548 | 0.81 | ALDH1A1 (0.41) | GABRG2GABRB3GABRA5BUB1KDM4E | |
| SCHEMBL31194316 | 0.81 | MET (0.43) | GABRG2GABRB3GABRA5BUB1KDM4E | |
| SCHEMBL27361311 | 0.79 | MET (0.46) | GABRG2GABRB3GABRA5BUB1KDM4E | |
| SCHEMBL29650289 | 0.78 | MET (0.39) | GABRG2GABRB3GABRA5BUB1KDM4E | |
| SCHEMBL19707129 | 0.78 | MET (0.39) | GABRG2GABRB3GABRA5BUB1KDM4E | |
| SCHEMBL28523293 | 0.76 | GRIN2B (0.61) | GRIN2BGRIN1 | |
| SCHEMBL759396 | 0.74 | SLC22A12 (0.48) | BUB1KDM4EALDH1A1PIK3CDABL1 | |
| SCHEMBL29962730 | 0.74 | SLC22A12 (0.48) | BUB1KDM4EALDH1A1PIK3CDABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175557-A1 | CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYL-SULFOXIME-PYRIDINE DERIVATIVES | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2024-08-29 | — | — | WO | disclosed |