Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18592788 | 0.83 | RAB9A (0.40) | MAPTSMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL7697974 | 0.75 | KEAP1 (0.42) | L3MBTL1 | |
| SCHEMBL344424 | 0.74 | — | — | |
| SCHEMBL2561694 | 0.74 | CAPN1 (0.46) | MAPTSMN1; SMN2RAB9ALMNATP53 | |
| SCHEMBL21576133 | 0.73 | CYP1A2 (0.34) | SMN1; SMN2HPGDKDM4E | |
| SCHEMBL19051511 | 0.73 | LMNA (0.50) | SMN1; SMN2LMNATSHR | |
| Phosphoric Acid SCHEMBL2022831 | 0.73 | BACE1 (0.32) | MAPTSMN1; SMN2LMNATSHRKDM4E | |
| SCHEMBL5160608 | 0.72 | RAB9A (0.39) | MAPTSMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL14233697 | 0.72 | NPSR1 (0.50) | MAPTSMN1; SMN2HPGDLMNATP53 | |
| SCHEMBL8606227 | 0.72 | ALOX5 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024050433-A1 | ALLOSTERIC MODULATORS OF ANDROGEN RECEPTOR COACTIVATOR RECRUITMENT FOR CRPC THERAPY | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2024-03-07 | — | — | WO | disclosed |