Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | ALPG | P10696 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505530 | 0.88 | L3MBTL1 (0.61) | LMNASMN1; SMN2HPGDALPGALDH1A1 | |
| SCHEMBL7202862 | 0.84 | L3MBTL1 (0.55) | LMNASMN1; SMN2HPGDALPGALDH1A1 | |
| SCHEMBL4461300 | 0.84 | L3MBTL1 (0.50) | LMNASMN1; SMN2HPGDALPGALDH1A1 | |
| SCHEMBL7198885 | 0.83 | CES2 (0.47) | LMNASMN1; SMN2HPGDALPGALDH1A1 | |
| SCHEMBL7198527 | 0.83 | TDP1 (0.47) | LMNASMN1; SMN2HPGDALPGALDH1A1 | |
| SCHEMBL6176444 | 0.81 | LTA4H (0.50) | LMNASMN1; SMN2HPGDALPGALDH1A1 | |
| SCHEMBL10978426 | 0.80 | LMNA (0.53) | LMNASMN1; SMN2HPGDALPGALDH1A1 | |
| SCHEMBL14519387 | 0.80 | L3MBTL1 (0.49) | LMNASMN1; SMN2HPGDALPGALDH1A1 | |
| SCHEMBL7200938 | 0.79 | TDP1 (0.50) | LMNASMN1; SMN2HPGDALPGALDH1A1 | |
| SCHEMBL8992867 | 0.79 | L3MBTL1 (0.50) | LMNASMN1; SMN2HPGDALPGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003042148-A2 | PROCESS FOR PRODUCING BISBENZIL COMPOUNDS | SHOWA DENKO K. K. (JP) | 2003-05-22 | — | — | WO | disclosed |