Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MLKL | Q8NB16 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9315620 | 0.76 | AGTR1 (0.35) | NCF1CYP1A2 | |
| Hydrochloric Acid SCHEMBL9314540 | 0.75 | AGTR1 (0.34) | NCF1CYP1A2 | |
| Hydrochloric Acid SCHEMBL27646680 | 0.74 | MLKL (0.33) | MLKLHPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL27311740 | 0.72 | NCF1 (0.33) | NCF1CYP1A2LMNAHPGDSMN1; SMN2 | |
| SCHEMBL12283481 | 0.69 | NCF1 (0.56) | NCF1CYP1A2LMNASMN1; SMN2MEN1 | |
| SCHEMBL28684747 | 0.68 | BRAF (0.50) | NCF1CYP1A2LMNAHPGDSMN1; SMN2 | |
| SCHEMBL6635318 | 0.66 | AGTR1 (0.54) | — | |
| Hydrochloric Acid SCHEMBL7840690 | 0.65 | AGTR1 (0.53) | — | |
| SCHEMBL29877118 | 0.64 | LMNA (0.64) | NCF1CYP1A2LMNAHPGDSMN1; SMN2 | |
| SCHEMBL266444 | 0.64 | LMNA (0.64) | NCF1CYP1A2LMNAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1058965-A | The method for preparing new quinoline | ICI PLC (GB) | 1992-02-26 | — | — | CN | disclosed |