Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2908390 | 0.97 | LMNA (0.45) | LMNAALDH1A1CYP1A2ATMEPHX1 | |
| SCHEMBL2691986 | 0.86 | LMNA (0.47) | LMNACYP1A2EPHX1PARP15PARP10 | |
| SCHEMBL2349782 | 0.83 | CYP1A2 (0.52) | ALDH1A1CYP1A2EPHX1SMN1; SMN2NAAA | |
| SCHEMBL27517798 | 0.81 | GNAI3 (0.41) | ALDH1A1ATMEPHX1 | |
| SCHEMBL1669840 | 0.80 | LMNA (0.59) | LMNAEPHX1PARP15PARP10NAAA | |
| SCHEMBL3117465 | 0.79 | ALDH1A1 (0.52) | LMNAALDH1A1ATM | |
| SCHEMBL27313505 | 0.79 | CHRNB2 (0.43) | LMNAALDH1A1ATMEPHX1SMN1; SMN2 | |
| SCHEMBL23129641 | 0.78 | LMNA (0.57) | LMNAEPHX1PARP15PARP10NAAA | |
| SCHEMBL1672623 | 0.78 | LMNA (0.55) | LMNAEPHX1PARP15PARP10 | |
| SCHEMBL1439244 | 0.77 | ALDH1A1 (0.54) | LMNAALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1068333-A | Has hydrazine analog derivative of pharmacologically active and preparation method thereof | CIBA GEIGY AG (CH) | 1993-01-27 | — | — | CN | disclosed |