⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15305624 | 0.78 | CA2 (0.40) | — | |
| SCHEMBL1892678 | 0.77 | — | — | |
| SCHEMBL10040252 | 0.77 | CA2 (0.50) | — | |
| SCHEMBL595425 | 0.76 | CA5A (0.36) | — | |
| SCHEMBL27077550 | 0.75 | CA2 (0.53) | — | |
| SCHEMBL19293129 | 0.75 | PTGS1 (0.40) | — | |
| Ammonia Solution, Strong SCHEMBL1503479 | 0.75 | — | — | |
| SCHEMBL715712 | 0.75 | — | — | |
| SCHEMBL14264215 | 0.74 | CA2 (0.38) | — | |
| SCHEMBL2782961 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1060781-C | Phosphonootropic monoester nucleic acids, process for their preparation and their use | HOECHST AG (DE) | 2001-01-17 | — | — | CN | claimed |
| CN-1138588-A | Phosphonootropic monoester nucleic acids, process for their preparation and their use | HOECHST AG (DE) | 1996-12-25 | — | — | CN | claimed |
| CN-105358692-A | Antisense oligomers and conjugates targeting pcsk9 | ROCHE INNOVATION CT COPENHAGEN AS | 2016-02-24 | — | — | CN | disclosed |
| CN-105121452-A | Tricyclic nucleosides and oligomeric compounds prepared therefrom | UNIV BERN | 2015-12-02 | — | — | CN | disclosed |
| CN-104837996-A | Anti APOB antisense conjugate compounds | SANTARIS PHARMA AS | 2015-08-12 | — | — | CN | disclosed |
| CN-102119217-B | Novel lipid formulations for nucleic acid delivery | PROTIVA BIOTHERAPEUTICS INC | 2015-06-03 | — | — | CN | disclosed |
| CN-104321304-A | Trialkyl cationic lipids and methods of use thereof | PROTIVA BIOTHERAPEUTICS INC | 2015-01-28 | — | — | CN | disclosed |
| CN-104136451-A | Synthesis and use of nucleic acid compounds with conformationally constrained monomers | MARINA BIOTECH INC | 2014-11-05 | — | — | CN | disclosed |
| CN-104114571-A | Compositions and methods for silencing aldehyde dehydrogenase | PROTIVA BIOTHERAPEUTICS INC | 2014-10-22 | — | — | CN | disclosed |
| CN-101796062-B | 6-disubstituted bicyclic nucleic acid analogs | ISIS PHARMACEUTICALS INC | 2014-07-30 | — | — | CN | disclosed |
| CN-103492572-A | Compositions and methods for treating lung diseases and injuries | QUARK PHARMACEUTICALS INC | 2014-01-01 | — | — | CN | disclosed |
| CN-100558893-C | The adjusting that eIF4E expresses | ISIS PHARMACEUTICALS INC ELI L (US) | 2009-11-11 | — | — | CN | disclosed |
| CN-101517082-A | CpG oligonucleotide analogs containing hydrophobic T analogs with enhanced immunostimulatory activity | COLEY PHARM GMBH (DE) | 2009-08-26 | — | — | CN | disclosed |
| CN-101331231-A | Compounds and methods for peptide ribonucleic acid condensate particles for RNA therapeutics | NASTECH PHARM CO (US) | 2008-12-24 | — | — | CN | disclosed |
| CN-101310018-A | Combinations and methods using immunomodulatory oligodeoxynucleotides | PFIZER (US) | 2008-11-19 | — | — | CN | disclosed |
| CN-101263230-A | Pharmaceutical compositions for delivering ribonucleic acid to cells | NASTECH PHARM CO (US) | 2008-09-10 | — | — | CN | disclosed |
| CN-1984921-A | Modulation of survivin expression | ISIS PHARMACEUTICALS INC (US) | 2007-06-20 | — | — | CN | disclosed |
| CN-1852979-A | Modulation of eIF4E expression | ISIS PHARMACEUTICALS INC (US) | 2006-10-25 | — | — | CN | disclosed |
| CN-1514842-A | Processes of purifying oligonucleotides | ISISҩ�﹫˾ | 2004-07-21 | — | — | CN | disclosed |
| CN-1171112-A | Amino acid nucleic acids | ICN PHARMACEUTICALS CO (US) | 1998-01-21 | — | — | CN | disclosed |