Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | GRM8 | O00222 | 1/20 | 0.35 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 5/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2736393 | 0.81 | MAOA (0.50) | MAOAMAOBATMLMNAMEN1 | |
| SCHEMBL79265 | 0.76 | MAOA (0.48) | MAOAMAOBGRM8GRM7GRM4 | |
| SCHEMBL31545658 | 0.74 | LMNA (0.41) | MAOAMAOBGRM8GRM7GRM4 | |
| SCHEMBL3625458 | 0.70 | KEAP1 (0.67) | TAAR1KEAP1MPOHSPA5 | |
| SCHEMBL9633190 | 0.70 | CYP1A2 (0.51) | GRM8GRM7GRM4ATMLMNA | |
| SCHEMBL9719337 | 0.70 | MEN1 (0.45) | MAOAMAOBHTTATMLMNA | |
| SCHEMBL987688 | 0.70 | MPO (0.60) | TAAR1KEAP1MPOHSPA5 | |
| SCHEMBL2885969 | 0.70 | HTT (0.44) | MAOAMAOBGRM8GRM7HTT | |
| SCHEMBL30468688 | 0.69 | MPO (0.58) | TAAR1KEAP1MPOHSPA5 | |
| Potassium SCHEMBL30848210 | 0.69 | MPO (0.58) | TAAR1KEAP1MPOHSPA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090121627-A1 | AROMATIC CHALCOGEN COMPOUNDS AND THEIR USE | E. I. DU PONT DE NEMOURS AND COMPANY | 2009-05-14 | — | — | US | disclosed |