Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 16/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27364059 | 0.82 | LMNA (0.49) | KLKB1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL27364070 | 0.81 | KLKB1 (0.55) | KLKB1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL30755181 | 0.79 | L3MBTL1 (0.50) | KLKB1ALDH1A1LMNAMAPTPOLB | |
| SCHEMBL27379021 | 0.78 | GRM2 (0.52) | KLKB1ALDH1A1LMNAPOLB | |
| SCHEMBL752774 | 0.76 | LMNA (0.61) | KLKB1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL27364065 | 0.75 | KLKB1 (0.41) | KLKB1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL27364232 | 0.75 | KLKB1 (0.53) | KLKB1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL27373433 | 0.74 | HSD17B10 (0.53) | KLKB1ALDH1A1LMNAMAPTPOLB | |
| SCHEMBL27364061 | 0.73 | ADORA2B (0.47) | KLKB1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL13692389 | 0.73 | L3MBTL1 (0.54) | KLKB1ALDH1A1LMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026483-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |