Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SCD | O00767 | 3/20 | 0.43 |
| ▸ | SCD5 | Q86SK9 | 3/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27379738 | 0.86 | L3MBTL1 (0.51) | LMNAMAPTALDH1A1MAPK1HTT | |
| SCHEMBL752774 | 0.85 | LMNA (0.61) | LMNAMAPTALDH1A1MAPK1HTT | |
| SCHEMBL27379736 | 0.82 | GRM2 (0.55) | LMNAALDH1A1KLKB1L3MBTL1HSD17B10 | |
| SCHEMBL27364069 | 0.82 | KLKB1 (0.44) | LMNAMAPTALDH1A1MAPK1HTT | |
| SCHEMBL27364070 | 0.81 | KLKB1 (0.55) | LMNAMAPTALDH1A1MAPK1HTT | |
| SCHEMBL13692389 | 0.78 | L3MBTL1 (0.54) | LMNAMAPTALDH1A1MAPK1HTT | |
| SCHEMBL19300037 | 0.78 | HSD17B10 (0.51) | LMNAMAPTALDH1A1MAPK1HTT | |
| SCHEMBL27364065 | 0.78 | KLKB1 (0.41) | LMNAMAPTALDH1A1MAPK1HTT | |
| SCHEMBL17229366 | 0.77 | KLKB1 (0.51) | LMNAMAPTALDH1A1MAPK1HTT | |
| SCHEMBL27364232 | 0.77 | KLKB1 (0.53) | LMNAMAPTALDH1A1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026483-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |