Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 4/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568529 | 0.82 | DHFR (0.35) | DHFR | |
| SCHEMBL27364194 | 0.74 | PLAU (0.44) | DHFRPLAUBACE1SLC2A1 | |
| SCHEMBL3772999 | 0.65 | GRIN2D (0.58) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL16175487 | 0.64 | MAPT (0.56) | RAB9A | |
| SCHEMBL12501310 | 0.62 | L3MBTL1 (0.60) | RAB9A | |
| SCHEMBL8741155 | 0.61 | TSHR (0.43) | PLAUF2PLGPLATKLKB1 | |
| SCHEMBL10310301 | 0.61 | NPSR1 (0.69) | RAB9A | |
| SCHEMBL9543474 | 0.61 | DHFR (0.34) | DHFRSLC2A1 | |
| SCHEMBL1996357 | 0.61 | SIGMAR1 (0.57) | PLAUF2PLGKLKB1PRSS1 | |
| SCHEMBL8269124 | 0.60 | SIGMAR1 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1073175-A | Heterogeneous ring compound | WELLCOME FOUND (GB) | 1993-06-16 | — | — | CN | disclosed |