Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | ALDH5A1 | P51649 | 2/20 | 0.44 |
| ▸ | ABAT | P80404 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA3 | P07451 | 2/20 | 0.44 |
| ▸ | TYR | P14679 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28066941 | 0.78 | CES2 (0.48) | LMNAMAPTCA1CA2KMT2A | |
| SCHEMBL1403013 | 0.77 | TDP1 (0.54) | LMNAMAPTHPGDPKMCA1 | |
| SCHEMBL361345 | 0.72 | ALDH5A1 (0.62) | LMNAMAPTESR1HPGDHTT | |
| SCHEMBL162830 | 0.70 | PARP10 (0.74) | LMNAMAPTESR1HPGDHTT | |
| SCHEMBL28823636 | 0.70 | PARP10 (0.74) | LMNAMAPTESR1HPGDHTT | |
| Hydroquinone SCHEMBL8674228 | 0.70 | PARP10 (0.74) | LMNAMAPTESR1HPGDHTT | |
| SCHEMBL3628327 | 0.70 | MAPT (0.52) | LMNAMAPTESR1HPGDHTT | |
| Water SCHEMBL9413887 | 0.70 | ALDH5A1 (0.60) | LMNAMAPTESR1HPGDHTT | |
| SCHEMBL28195663 | 0.70 | LMNA (0.48) | LMNAMAPTESR1HPGDHTT | |
| Ammonia Solution, Strong SCHEMBL28805645 | 0.69 | PARP10 (0.71) | LMNAMAPTESR1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1051547-C | Beta-lactams derivative and its prep. and use | HOFFMANN LA ROCHE (CH) | 2000-04-19 | — | — | CN | claimed |
| CN-1132752-A | Beta-lactam derivatives, process for their preparation and their use | HOFFMANN LA ROCHE (CH) | 1996-10-09 | — | — | CN | claimed |
| CN-1051547-C | Beta-lactams derivative and its prep. and use | HOFFMANN LA ROCHE (CH) | 2000-04-19 | — | — | CN | disclosed |
| CN-1132752-A | Beta-lactam derivatives, process for their preparation and their use | HOFFMANN LA ROCHE (CH) | 1996-10-09 | — | — | CN | disclosed |