Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | PYGL | P06737 | 2/20 | 0.32 |
| ▸ | DHODH | Q02127 | 6/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8998058 | 0.92 | LMNA (0.34) | LMNANPSR1ALDH1A1NPC1RAB9A | |
| SCHEMBL9835450 | 0.90 | NPSR1 (0.43) | LMNANPSR1ALDH1A1NPC1RAB9A | |
| SCHEMBL9835444 | 0.87 | RORC (0.39) | LMNANPSR1ALDH1A1NPC1RAB9A | |
| SCHEMBL9834362 | 0.87 | LMNA (0.34) | LMNANPSR1ALDH1A1NPC1RAB9A | |
| SCHEMBL8998061 | 0.83 | ALDH1A1 (0.35) | LMNANPSR1ALDH1A1NPC1RAB9A | |
| SCHEMBL8998045 | 0.83 | SCN9A (0.42) | TSHR | |
| SCHEMBL8998088 | 0.80 | LMNA (0.34) | LMNANPSR1ALDH1A1NPC1RAB9A | |
| SCHEMBL8998090 | 0.80 | LMNA (0.34) | LMNANPSR1ALDH1A1NPC1RAB9A | |
| SCHEMBL8998070 | 0.80 | L3MBTL1 (0.46) | LMNANPSR1ALDH1A1NPC1RAB9A | |
| SCHEMBL9835963 | 0.80 | RORC (0.39) | LMNANPSR1ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344953-A | Fluorobenzene derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1994-09-06 | — | — | US | disclosed |