SCHEMBL27366111

SCHEMBL27366111

CN(C)CCc1cccc2ccc(Cl)cc12

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.64
TAAR1 Q96RJ0 4/20 0.51
MTNR1A P48039 1/20 0.46
MTNR1B P49286 1/20 0.46
ADRA2A P08913 1/20 0.46
ADRA2B P18089 1/20 0.46
ADRA2C P18825 1/20 0.46
HTR7 P34969 1/20 0.46
HTR2B P41595 1/20 0.46
HTR6 P50406 1/20 0.46
SLC6A4 P31645 1/20 0.44
OPRL1 P41146 3/20 0.44
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27367754 0.85 HTR2A (0.52) HTR2ATAAR1MTNR1AMTNR1BHTR2B
SCHEMBL27366117 0.83 HTR2A (0.54) HTR2ATAAR1MTNR1AMTNR1B
SCHEMBL27366183 0.81 HTR2A (0.64) HTR2ATAAR1MTNR1AMTNR1BHTR6
SCHEMBL28788751 0.81 HTR2A (0.64) HTR2AMTNR1AMTNR1BHTR7HTR2B
SCHEMBL605212 0.79 HTR2A (0.61) HTR2ATAAR1HTR2BALDH1A1MAPT
SCHEMBL8021734 0.78 HTR2A (1.00) HTR2AMTNR1AMTNR1BHTR7HTR2B
SCHEMBL31331983 0.78 HTR2A (1.00) HTR2AMTNR1AMTNR1BHTR7HTR2B
SCHEMBL27366935 0.78 CYP2A6 (0.41) HTR2AMTNR1AMTNR1BMAPT
SCHEMBL27366938 0.78 MTNR1A (0.41) HTR2AMTNR1AMTNR1BHTR2BMAPT
SCHEMBL18015817 0.78 CYP2A6 (0.43) MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333371-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-10-30 US disclosed
EP-4532462-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-04-09 EP disclosed
CN-119384406-A Compounds of formula (I) 赛洛私人有限公司 2025-01-28 CN disclosed
WO-2023230649-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-12-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250333371-A1 COMPOUNDS SDHA, PYGB, SLC18A2 HTR2A 225/4885TAAR1 647/4885MTNR1A 1247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.