SCHEMBL27366117

SCHEMBL27366117

CN(CCc1cccc2ccc(Cl)cc12)C1CC1

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.54
CHIT1 Q13231 3/20 0.43
CHIA Q9BZP6 3/20 0.43
MTNR1A P48039 3/20 0.43
MTNR1B P49286 2/20 0.43
CHI3L1 P36222 1/20 0.40
CHI3L2 Q15782 1/20 0.40
NOS3 P29474 6/20 0.38
NOS1 P29475 6/20 0.38
NOS2 P35228 6/20 0.38
C5AR1 P21730 1/20 0.37
NPC1 O15118 1/20 0.37
LMNA P02545 1/20 0.37
RAB9A P51151 1/20 0.37
OPRM1 P35372 1/20 0.36
OPRK1 P41145 1/20 0.36
HCRTR1 O43613 1/20 0.36
TAAR1 Q96RJ0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27367140 0.84 HTR2A (0.54) HTR2AMTNR1AMTNR1BOPRM1OPRK1
SCHEMBL27365901 0.84 HTR2A (0.61) HTR2AMTNR1AMTNR1B
SCHEMBL27366111 0.83 HTR2A (0.64) HTR2AMTNR1AMTNR1BTAAR1
SCHEMBL27365899 0.82 HTR2A (0.71) HTR2AMTNR1AMTNR1B
SCHEMBL27367754 0.78 HTR2A (0.52) HTR2AMTNR1AMTNR1BHCRTR1TAAR1
SCHEMBL27366961 0.75 CHRM1 (0.54) NPC1RAB9AOPRK1
Fumaric Acid SCHEMBL31331964 0.75 HTR2A (0.48) HTR2AMTNR1AMTNR1B
SCHEMBL24776468 0.74 HTR2A (0.55) HTR2ACHIT1CHIACHI3L1CHI3L2
SCHEMBL25833470 0.74 TAAR1 (0.65) HTR2ACHIT1CHIACHI3L1CHI3L2
Fumaric Acid SCHEMBL31332068 0.74 MTNR1A (0.62) HTR2AMTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333371-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-10-30 US disclosed
EP-4532462-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-04-09 EP disclosed
CN-119384406-A Compounds of formula (I) 赛洛私人有限公司 2025-01-28 CN disclosed
WO-2023230649-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-12-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250333371-A1 COMPOUNDS SDHA, PYGB, SLC18A2 HTR2A 225/4885CHIT1 2690/4885CHIA 3381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.