SCHEMBL27366961

SCHEMBL27366961

CN(C(=O)Cc1cccc2ccc(Cl)cc12)C1CC1

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.54
SIGMAR1 Q99720 2/20 0.47
CCR5 P51681 4/20 0.47
PYGL P06737 6/20 0.44
OPRK1 P41145 1/20 0.41
KMT2A Q03164 2/20 0.41
NPC1 O15118 1/20 0.41
F10 P00742 3/20 0.41
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27367147 0.86 SIGMAR1 (0.48) CHRM1SIGMAR1CCR5OPRK1KMT2A
SCHEMBL27529191 0.85 SIGMAR1 (0.47) CHRM1SIGMAR1CCR5OPRK1KMT2A
SCHEMBL27553023 0.85 SIGMAR1 (0.47) CHRM1SIGMAR1CCR5OPRK1KMT2A
SCHEMBL27366400 0.83 MTNR1A (0.57)
SCHEMBL5236753 0.77 MEN1 (0.47) KMT2AMEN1
SCHEMBL27366117 0.75 HTR2A (0.54) OPRK1NPC1RAB9A
SCHEMBL31332133 0.75 TDP1 (0.64) CHRM1KMT2AMEN1
SCHEMBL3581821 0.75 TDP1 (0.64) CHRM1KMT2AMEN1
SCHEMBL2405208 0.74 SIGMAR1 (0.60) CHRM1SIGMAR1CCR5PYGLOPRK1
SCHEMBL9711167 0.74 MEN1 (0.47) KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333371-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-10-30 US disclosed
EP-4532462-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-04-09 EP disclosed
CN-119384406-A Compounds of formula (I) 赛洛私人有限公司 2025-01-28 CN disclosed
WO-2023230649-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-12-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250333371-A1 COMPOUNDS SDHA, PYGB, SLC18A2 CHRM1 870/4885SIGMAR1 623/4885CCR5 4474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.