Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | CMA1 | P23946 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LPO | P22079 | 3/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | AGXT | P21549 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28328915 | 0.85 | SMN1; SMN2 (0.46) | SIGMAR1KDM4EALDH1A1LMNATP53 | |
| SCHEMBL28839843 | 0.81 | SIGMAR1 (0.46) | SIGMAR1CMA1KDM4EALDH1A1TAAR1 | |
| Hydrochloric Acid SCHEMBL27604313 | 0.80 | SIGMAR1 (0.45) | SIGMAR1CMA1KDM4EALDH1A1TAAR1 | |
| SCHEMBL27973953 | 0.78 | MRGPRX4 (0.47) | HTR1ADRD2MEN1KMT2A | |
| SCHEMBL28328916 | 0.78 | SIGMAR1 (0.43) | SIGMAR1CMA1KDM4EALDH1A1TAAR1 | |
| SCHEMBL28862078 | 0.77 | SIGMAR1 (0.50) | SIGMAR1KDM4EALDH1A1TAAR1GAA | |
| SCHEMBL28234340 | 0.77 | DRD2 (0.43) | KDM4ETAAR1LMNAMAPTDRD2 | |
| SCHEMBL5671275 | 0.76 | SIGMAR1 (0.43) | SIGMAR1CMA1ALDH1A1LMNAPOLB | |
| SCHEMBL28169069 | 0.75 | APLNR (0.50) | KDM4EALDH1A1GAALMNAMAPT | |
| SCHEMBL1011075 | 0.75 | LPO (0.54) | SIGMAR1CMA1KDM4EALDH1A1LPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1052305-A | New pyridine derivate, contain their pharmaceutical composition and preparation method thereof | RICHTER GEDEON VEGYESZET (HU) | 1991-06-19 | — | — | CN | claimed |
| CN-1052305-A | New pyridine derivate, contain their pharmaceutical composition and preparation method thereof | RICHTER GEDEON VEGYESZET (HU) | 1991-06-19 | — | — | CN | disclosed |