Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 6/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10207829 | 0.89 | ALDH1A1 (0.42) | — | |
| SCHEMBL12309578 | 0.88 | — | — | |
| SCHEMBL2736677 | 0.87 | SMN1; SMN2 (0.43) | MAOBMAOASLC26A4KMT2A | |
| SCHEMBL2736960 | 0.86 | GABRA1 (0.41) | — | |
| SCHEMBL10208272 | 0.86 | POLB (0.39) | — | |
| SCHEMBL2736994 | 0.85 | POLB (0.38) | — | |
| SCHEMBL10207673 | 0.85 | PSEN1 (0.38) | TP53KMT2AMAPK1 | |
| SCHEMBL2736652 | 0.85 | MAPT (0.37) | TP53KMT2A | |
| SCHEMBL2736633 | 0.84 | KDM4E (0.39) | KMT2A | |
| SCHEMBL10207266 | 0.84 | POLB (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402314-A1 | (Aza)indole derivative and use thereof for medical purposes | Kissei Pharmaceutical Co., Ltd. (JP) | 2012-01-04 | — | — | EP | disclosed |