Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12309575 | 0.88 | — | — | |
| SCHEMBL10207829 | 0.87 | ALDH1A1 (0.42) | SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL2736670 | 0.87 | MCHR1 (0.41) | SLC26A4KMT2AMAOAMAOB | |
| SCHEMBL2736633 | 0.86 | KDM4E (0.39) | SMN1; SMN2MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL2736960 | 0.85 | GABRA1 (0.41) | — | |
| SCHEMBL10208272 | 0.85 | POLB (0.39) | — | |
| SCHEMBL10207673 | 0.83 | PSEN1 (0.38) | SMN1; SMN2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL2736994 | 0.83 | POLB (0.38) | — | |
| SCHEMBL2736652 | 0.83 | MAPT (0.37) | SMN1; SMN2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10207266 | 0.83 | POLB (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402314-A1 | (Aza)indole derivative and use thereof for medical purposes | Kissei Pharmaceutical Co., Ltd. (JP) | 2012-01-04 | — | — | EP | disclosed |