SCHEMBL27366916

SCHEMBL27366916

CCOC(=O)CC1=CCCc2ccc(Cl)cc21

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.42
BRD4 O60885 1/20 0.42
POLB P06746 1/20 0.41
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
HPGD P15428 1/20 0.40
LMNA P02545 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
KDM4E B2RXH2 2/20 0.39
ALDH1A1 P00352 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
GAA P10253 1/20 0.39
ALOX15 P16050 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
RAB9A P51151 1/20 0.38
USP2 O75604 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24821194 0.84 KDM4C (0.45) MAPTBRD4MEN1KMT2ALMNA
SCHEMBL8515359 0.84 MPO (0.51) MAPTBRD4KMT2AHPGDALDH1A1
SCHEMBL7403188 0.82 KDM4E (0.47) BRD4HPGDTDP1KDM4EALDH1A1
SCHEMBL31618140 0.76 MPO (0.42) MAPTBRD4MEN1KMT2ALMNA
SCHEMBL10530875 0.76 MPO (0.42) MAPTBRD4MEN1KMT2AHPGD
SCHEMBL9482430 0.75 MPO (0.64) MAPTBRD4TDP1KDM4ESMN1; SMN2
SCHEMBL29273744 0.75 KMT2A (0.40) MAPTPOLBMEN1KMT2AHPGD
SCHEMBL19985029 0.75 ALDH1A1 (0.45) BRD4MEN1KMT2AHPGDTDP1
SCHEMBL11581498 0.72 GSTP1 (0.50) MAPTBRD4MEN1KMT2AHPGD
SCHEMBL2594098 0.72 NQO2 (0.42) MAPTBRD4POLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333371-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-10-30 US disclosed
EP-4532462-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-04-09 EP disclosed
WO-2023230649-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-12-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250333371-A1 COMPOUNDS SDHA, PYGB, SLC18A2 MAPT 224/4885BRD4 3733/4885POLB 1532/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.