SCHEMBL20243993

SCHEMBL20243993

CCOC(=O)C1CCc2cc(C(=O)ONC)ccc2C1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.43
DRD2 P14416 1/20 0.42
DRD3 P35462 1/20 0.42
HTT P42858 2/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TSHR P16473 1/20 0.38
RAB9A P51151 1/20 0.38
ALDH1A1 P00352 2/20 0.38
KMT2A Q03164 1/20 0.38
GLA P06280 1/20 0.38
POLB P06746 1/20 0.38
FAAH O00519 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15946394 0.89 DRD3 (0.51) KDM4EDRD2DRD3HTTGAA
SCHEMBL27367039 0.84 ALDH1A1 (0.45) KDM4EDRD2DRD3HTTGAA
SCHEMBL27367050 0.81 DRD2 (0.43) KDM4EDRD2DRD3HTTMAPT
SCHEMBL20427965 0.81 FAAH (0.34) DRD2DRD3FAAH
SCHEMBL16171627 0.80 ALDH1A1 (0.43) KDM4EDRD2DRD3ALDH1A1POLB
SCHEMBL629772 0.79 OPRK1 (0.48) KDM4EDRD2DRD3MAPTALDH1A1
SCHEMBL10529754 0.78 MAPK1 (0.46) KDM4EGAAMAPTTSHRALDH1A1
SCHEMBL21383104 0.78 SHMT2 (0.46) KDM4EDRD2DRD3GAAMAPT
SCHEMBL30437653 0.78 MAPK1 (0.46) KDM4EGAAMAPTTSHRALDH1A1
SCHEMBL15866398 0.78 ESR1 (0.47) DRD2DRD3MAPTTSHRRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9994382-B2 Oxygen-absorbing medical multilayer container and method for storing biological medicine MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2018-06-12 US disclosed