Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27367230 | 0.81 | CYP1A2 (0.38) | AOC3CYP2D6MEN1CYP1A2TSHR | |
| SCHEMBL8770867 | 0.73 | ALDH1A1 (0.42) | SLC6A3LMNA | |
| SCHEMBL8770874 | 0.72 | APP (0.42) | CYP2D6SLC6A2SLC6A3 | |
| SCHEMBL8770886 | 0.72 | L3MBTL1 (0.38) | CYP2D6HIF1AADRB2LMNA | |
| SCHEMBL8770891 | 0.71 | MTNR1A (0.50) | CYP1A2TSHRKMT2AHIF1AACHE | |
| SCHEMBL8770863 | 0.70 | L3MBTL1 (0.66) | AOC3 | |
| SCHEMBL8770937 | 0.70 | AOC3 (0.42) | AOC3CYP2D6ADRB2 | |
| SCHEMBL5922341 | 0.70 | FFAR1 (0.40) | CYP2D6TSHRLMNA | |
| SCHEMBL8770922 | 0.70 | AOC3 (0.42) | AOC3CYP2D6MEN1CYP1A2TSHR | |
| SCHEMBL8770939 | 0.70 | NPC1 (0.39) | CYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049929-A2 | PANNEXIN-1 MODULATORS AND METHODS OF TREATING DISORDERS IN WHICH PANNEXIN-1 IS IMPLICATED | PANNEX THERAPEUTICS INC. (US) | 2024-03-07 | — | — | WO | disclosed |