Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | F2R | P25116 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770922 | 0.84 | AOC3 (0.42) | LMNA | |
| SCHEMBL8903606 | 0.83 | GABBR2 (0.42) | ALDH1A1LMNAHTTSMN1; SMN2SLC6A3 | |
| SCHEMBL8770872 | 0.83 | LMNA (0.49) | ALDH1A1LMNAHTTSMN1; SMN2SLC6A3 | |
| SCHEMBL8770902 | 0.82 | L3MBTL1 (0.43) | — | |
| SCHEMBL1457021 | 0.82 | SLC6A3 (0.46) | ALDH1A1LMNAHTTSMN1; SMN2SLC6A3 | |
| SCHEMBL8903295 | 0.82 | ALDH1A1 (0.38) | ALDH1A1LMNAHTTSMN1; SMN2SLC6A3 | |
| SCHEMBL8770893 | 0.81 | APP (0.39) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL8770874 | 0.81 | APP (0.42) | SLC6A3 | |
| SCHEMBL8770886 | 0.81 | L3MBTL1 (0.38) | ALDH1A1LMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL30524647 | 0.80 | F2R (0.43) | ALDH1A1LMNAHTTSMN1; SMN2F2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |