Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27367215 | 0.81 | AOC3 (0.36) | CYP1A2CYP2D6MEN1TSHRKMT2A | |
| SCHEMBL8770867 | 0.78 | ALDH1A1 (0.42) | — | |
| SCHEMBL8770874 | 0.77 | APP (0.42) | CYP2D6 | |
| SCHEMBL8770886 | 0.77 | L3MBTL1 (0.38) | CYP2D6HIF1AL3MBTL1 | |
| SCHEMBL12600107 | 0.77 | PRMT3 (0.35) | CYP2D6HIF1ACYP2A6 | |
| SCHEMBL8770891 | 0.76 | MTNR1A (0.50) | CYP1A2TSHRKMT2AHIF1AL3MBTL1 | |
| SCHEMBL16811746 | 0.75 | APP (0.49) | CYP1A2TSHRL3MBTL1CYP2C9 | |
| SCHEMBL8770863 | 0.75 | L3MBTL1 (0.66) | L3MBTL1AOC3 | |
| SCHEMBL8770922 | 0.75 | AOC3 (0.42) | CYP1A2CYP2D6MEN1TSHRKMT2A | |
| SCHEMBL8770937 | 0.75 | AOC3 (0.42) | CYP2D6AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049929-A2 | PANNEXIN-1 MODULATORS AND METHODS OF TREATING DISORDERS IN WHICH PANNEXIN-1 IS IMPLICATED | PANNEX THERAPEUTICS INC. (US) | 2024-03-07 | — | — | WO | disclosed |