Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23818010 | 0.76 | FNIP1 (0.58) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL25455117 | 0.66 | CTNNB1 (0.48) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL2721422 | 0.66 | TRPM8 (0.67) | POLB | |
| SCHEMBL31647347 | 0.66 | TRPM8 (0.67) | POLB | |
| SCHEMBL4599642 | 0.61 | KMT2A (0.66) | RAB9ASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL10183731 | 0.60 | USP2 (0.39) | RAB9ASMN1; SMN2TSHRMAPK1HSD17B10 | |
| SCHEMBL21742226 | 0.60 | PTGDR2 (0.56) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL20456266 | 0.60 | ALDH1A1 (0.66) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL2729280 | 0.60 | TRPM8 (0.70) | POLB | |
| SCHEMBL14499604 | 0.60 | KMT2A (0.60) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049829-A2 | COMPOSITIONS AND METHODS FOR TREATING AND DETECTING CANCER | CASE WESTERN RESERVE UNIVERSITY (US) | 2024-03-07 | — | — | WO | disclosed |