Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 3/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | AADAC | P22760 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27362636 | 0.79 | RAB9A (0.37) | PDK1MAPK1HTTSMN1; SMN2TRPV1 | |
| SCHEMBL27368338 | 0.74 | POLB (0.41) | ALDH1A1CASR | |
| SCHEMBL23551763 | 0.65 | NAMPT (0.40) | — | |
| SCHEMBL24491308 | 0.64 | KDM1A (0.42) | ALDH1A1 | |
| SCHEMBL19951698 | 0.63 | SMN1; SMN2 (0.43) | PDK1KDRARCES2ABCB11 | |
| SCHEMBL1555605 | 0.63 | SMN1; SMN2 (0.43) | PDK1KDRARCES2ABCB11 | |
| SCHEMBL25557198 | 0.63 | BMP1 (0.31) | — | |
| SCHEMBL29311609 | 0.62 | CHRNB2 (0.38) | CNR2CYP1A2CYP2C9KCNH2SMN1; SMN2 | |
| SCHEMBL25561171 | 0.62 | HPGD (0.48) | ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL11879435 | 0.61 | ALDH1A1 (0.68) | PDK1KDRARCES2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026083-A1 | TARGETED PROTEIN DEGRADATION OF PARP14 FOR USE IN THERAPY | RIBON THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |