SCHEMBL27368422

SCHEMBL27368422

Cc1cccc(C2N=NN=N2)c1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.46
HTR2C P28335 3/20 0.44
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
HTR2A P28223 1/20 0.41
SLC6A4 P31645 1/20 0.41
HTR2B P41595 1/20 0.41
SLC6A3 Q01959 1/20 0.41
NPC1 O15118 1/20 0.41
HPN P05981 1/20 0.41
MAOB P27338 4/20 0.38
ALDH1A1 P00352 1/20 0.38
MAPK1 P28482 1/20 0.38
HDAC4 P56524 1/20 0.38
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
PBRM1 Q86U86 1/20 0.36
MAOA P21397 2/20 0.36
CYP19A1 P11511 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27470879 0.74 CYP3A4 (0.46) MEN1MAOBALDH1A1MAPK1LMNA
SCHEMBL27592652 0.74 KDM1A (0.47) HTR2CKMT2AMEN1HTR2AHTR2B
SCHEMBL27518914 0.72 MAOA (0.40) HTR2CHTR2AHTR2BALDH1A1HDAC4
SCHEMBL28523025 0.72 CASP1 (0.44) KMT2AMEN1NPC1MAOBALDH1A1
SCHEMBL27455781 0.72 ACHE (0.42) ACHEHTR2CKMT2AMEN1HTR2A
SCHEMBL4486696 0.71 TSHR (0.36) HTR2CHTR2BSLC6A3MAOBMAPK1
SCHEMBL6151708 0.70 ACHE (0.52) ACHEHTR2CKMT2AMEN1HTR2A
SCHEMBL1515269 0.68 HTR2C (0.74) ACHEHTR2CKMT2AMEN1HTR2A
SCHEMBL30717247 0.67 ACHE (0.48) ACHEHTR2CKMT2AMEN1HTR2A
SCHEMBL5852622 0.67 ACHE (0.48) ACHEHTR2CKMT2AMEN1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102822306-B Adhesive composition, adhesive tape, method for processing semiconductor wafer, and method for manufacturing TSV wafer SEKISUI CHEMICAL CO LTD 2015-02-11 CN disclosed
CN-102822306-A Adhesive composition, adhesive tape, method for processing semiconductor wafer, and method for manufacturing TSV wafer SEKISUI CHEMICAL CO LTD 2012-12-12 CN disclosed
CN-1568187-A 2H-2,3-dinitrogen phenodiazine-1-ketone and using method thereof ICOS CORP (US) 2005-01-19 CN disclosed
CN-1128617-C Prepration method for medicinal composition containing triazolyl derivative MERCK SHARP & DOHME (GB) 2003-11-26 CN disclosed
CN-1064485-A IMIDAZOLE, TRIAZOLE AND TETRAZOLE DERIVATIVES MERCK SHARP & DOHME (GB) 1992-09-16 CN disclosed