Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.45 |
| ▸ | HTR1E | P28566 | 2/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27361339 | 1.00 | BDKRB2 (0.48) | BDKRB2ALOX5HDAC6EPHX1HTR1E | |
| SCHEMBL10006210 | 0.84 | NPC1 (0.46) | ALOX5HDAC6EPHX1HTR1ES1PR3 | |
| SCHEMBL7013582 | 0.84 | ALOX5 (0.45) | ALOX5HDAC6EPHX1HTR1ES1PR3 | |
| SCHEMBL1069660 | 0.84 | ALOX5 (0.45) | ALOX5HDAC6EPHX1HTR1ES1PR3 | |
| SCHEMBL8634916 | 0.83 | CHRM3 (0.47) | ALOX5HDAC6EPHX1HTR1ES1PR3 | |
| SCHEMBL27372606 | 0.82 | SLC6A3 (0.59) | SLC6A2SLC6A3 | |
| SCHEMBL27388408 | 0.81 | CHRM3 (0.46) | ALOX5HDAC6EPHX1HTR1ES1PR3 | |
| SCHEMBL27483589 | 0.81 | CHRM3 (0.46) | ALOX5HDAC6EPHX1HTR1ES1PR3 | |
| SCHEMBL8636307 | 0.80 | CHRM3 (0.49) | ALOX5HDAC6EPHX1HTR1ES1PR3 | |
| SCHEMBL4242909 | 0.80 | ALOX5 (0.49) | ALOX5HDAC6HTR1ES1PR3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102083803-B | Oxocyclic substituted carboxylic acid derivatives and their use | BAYER IP GMBH | 2015-02-18 | — | — | CN | disclosed |
| CN-1330065-A | Intermediates for the preparation of enantiomerically pure indole carboxylic acids and reactive derivatives thereof | BAYER AG (DE) | 2002-01-09 | — | — | CN | disclosed |
| CN-1312246-A | Process for preparing carboxylic acid | BAYER AG (DE) | 2001-09-12 | — | — | CN | disclosed |
| CN-1067394-C | Process for the preparation of enantiomerically pure indole-carboxylic acids and their reactive derivatives | BAYER AG (DE) | 2001-06-20 | — | — | CN | disclosed |
| CN-1067393-C | Novel pyrimido [1, 2-a ] indoles | BAYER AG (DE) | 2001-06-20 | — | — | CN | disclosed |
| CN-1184109-A | Process for the preparation of enantiomerically pure cycloalkanolindoleindole-and azaindole-and pyrimido [1, 2-a ] -indole-carboxylic acids and active derivatives thereof | BAYER AG (DE) | 1998-06-10 | — | — | CN | disclosed |