Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 4/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HTR1E | P28566 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8636307 | 0.91 | CHRM3 (0.49) | CHRM3ALOX5HDAC6HTR1EKMT2A | |
| SCHEMBL27483589 | 0.86 | CHRM3 (0.46) | CHRM3ALOX5HDAC6HTR1EKMT2A | |
| SCHEMBL27388408 | 0.86 | CHRM3 (0.46) | CHRM3ALOX5HDAC6HTR1EKMT2A | |
| SCHEMBL7013582 | 0.83 | ALOX5 (0.45) | CHRM3ALOX5HDAC6HTR1EKMT2A | |
| SCHEMBL1069660 | 0.83 | ALOX5 (0.45) | CHRM3ALOX5HDAC6HTR1EKMT2A | |
| SCHEMBL27361339 | 0.83 | BDKRB2 (0.48) | CHRM3ALOX5HDAC6HTR1EKMT2A | |
| SCHEMBL27368748 | 0.83 | BDKRB2 (0.48) | CHRM3ALOX5HDAC6HTR1EKMT2A | |
| SCHEMBL10006210 | 0.83 | NPC1 (0.46) | CHRM3ALOX5HDAC6HTR1EKMT2A | |
| SCHEMBL4242909 | 0.78 | ALOX5 (0.49) | CHRM3ALOX5HDAC6HTR1EKMT2A | |
| SCHEMBL69127 | 0.78 | HTR1E (0.65) | CHRM3ALOX5HDAC6HTR1EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776964-A | HYPOTENSIVE AGENTS; ANTICHOLESTEROL AGENTS; CARDIOVASCULAR DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-07-07 | — | — | US | disclosed |
| US-5521206-A | HYPOTENSIVE AGENTS, TREATMENT OF ATHEROSCLEROSIS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-05-28 | — | — | US | disclosed |