SCHEMBL28433779

SCHEMBL28433779

Cc1ccc(S(=O)(=O)C2CNCCO2)cc1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.39
GAA P10253 1/20 0.37
CYP2D6 P10635 1/20 0.36
HRH1 P35367 1/20 0.36
KCNH2 Q12809 1/20 0.36
MMP13 P45452 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA3 P07451 1/20 0.35
CA6 P23280 1/20 0.35
CA5A P35218 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA5B Q9Y2D0 1/20 0.35
SLC12A2 P55011 1/20 0.35
SLC12A5 Q9H2X9 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14775611 0.84 HTR6 (0.37) HTR6GAAMMP13MEN1KMT2A
SCHEMBL10781545 0.84 MAPT (0.44)
SCHEMBL5821011 0.84 MMP2 (0.33) MMP13CA1CA2
SCHEMBL27828787 0.84 DRD2 (0.40) KCNH2MMP13CA12CA1CA2
SCHEMBL4771959 0.84 GLA (0.35) CA2
SCHEMBL6422590 0.84 SLC6A2 (0.38) HTR6CYP2D6KCNH2
SCHEMBL28274223 0.84 CA12 (0.40) CA12CA1CA2CA9
SCHEMBL28246223 0.82 CTSC (0.39) CA12CA1CA2CA9
SCHEMBL3866888 0.81 DRD2 (0.34)
SCHEMBL16345364 0.81 ENPP2 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111440132-B Novel method for preparing oxygen heterocyclic compound by ionic liquid catalysis 中国科学院化学研究所 2022-02-01 CN claimed
CN-111440132-A Novel method for preparing oxygen heterocyclic compound by ionic liquid catalysis 中国科学院化学研究所 2020-07-24 CN claimed
CN-111440132-B Novel method for preparing oxygen heterocyclic compound by ionic liquid catalysis 中国科学院化学研究所 2022-02-01 CN disclosed
CN-111440132-A Novel method for preparing oxygen heterocyclic compound by ionic liquid catalysis 中国科学院化学研究所 2020-07-24 CN disclosed