SCHEMBL27375183

SCHEMBL27375183

CCc1c(N)ccc(N=Nc2ccccc2C(=O)O)c1CC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDE P14735 1/20 0.47
CCNE2 O96020 1/20 0.46
CCNE1 P24864 1/20 0.46
CDK2 P24941 1/20 0.46
MYC P01106 1/20 0.46
MEN1 O00255 10/20 0.45
KMT2A Q03164 10/20 0.45
MAPT P10636 7/20 0.45
NPSR1 Q6W5P4 3/20 0.45
GAA P10253 2/20 0.45
PSMD14 O00487 1/20 0.45
HSP90AA1 P07900 1/20 0.45
MMP2 P08253 1/20 0.45
THRB P10828 1/20 0.45
MAPK1 P28482 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
POLB P06746 3/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
ALDH1A1 P00352 2/20 0.42
HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29145795 0.81 GAA (0.47) IDECCNE2CCNE1CDK2MYC
SCHEMBL28865978 0.78 MEN1 (0.58) IDECCNE2CCNE1CDK2MYC
Phthalic Acid SCHEMBL21957758 0.77 ALDH1A1 (0.47) MYCKMT2AMAPTGAAMMP2
SCHEMBL7155929 0.76 GAA (0.61) IDECCNE2CCNE1CDK2MYC
SCHEMBL68503 0.76 IDE (0.71) IDECCNE2CCNE1CDK2MYC
SCHEMBL68504 0.76 IDE (0.71) IDECCNE2CCNE1CDK2MYC
SCHEMBL11128772 0.75 ALDH1A1 (0.47) MEN1KMT2AGAAPOLBL3MBTL1
SCHEMBL8743511 0.74 GABRP (0.49) MEN1KMT2AMAPTGAAMMP2
SCHEMBL29145799 0.73 IDE (0.49) IDECCNE2CCNE1CDK2MYC
SCHEMBL1126873 0.73 MMP2 (0.55) MYCMAPTGAAMMP2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1084473-C Reagent for analysing leucocyte SYSMEX CORP (JP) 2002-05-08 CN disclosed
CN-1127886-A Reagent for analysing leucocyte TOA MEDICAL ELECTRONICS (JP) 1996-07-31 CN disclosed