Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CENPE | Q02224 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PKLR | P30613 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | NEK1 | Q96PY6 | 2/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27539886 | 0.89 | ADORA3 (0.41) | PKMTACR1TP53HTT | |
| SCHEMBL27371705 | 0.82 | CENPE (0.48) | CENPETACR1GRIA2GRIA4MAPK14 | |
| SCHEMBL27399207 | 0.79 | PKM (0.35) | CENPEPKMPKLRRXFP1NEK1 | |
| SCHEMBL27364098 | 0.79 | TP53 (0.35) | CENPETACR1GRIA2GRIA4MAPK14 | |
| SCHEMBL7852329 | 0.78 | TP53 (0.41) | CENPEPKMTP53HTT | |
| SCHEMBL27530229 | 0.77 | GAA (0.34) | PKMPKLRRXFP1TACR1TP53 | |
| SCHEMBL7850622 | 0.76 | GRIA2 (0.44) | CENPEPKMPKLRRXFP1TACR1 | |
| SCHEMBL7849856 | 0.70 | TACR1 (0.66) | RXFP1TACR1TP53HTT | |
| SCHEMBL27364100 | 0.70 | PKM (0.35) | CENPEPKMPKLRTACR1NEK1 | |
| SCHEMBL7850615 | 0.69 | GRIA2 (0.44) | CENPEPKMPKLRTACR1GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1052004-C | Heterocyclic compounds, their production and use | TALCEDA CHEMICAL IND LTD (JP) | 2000-05-03 | — | — | CN | disclosed |
| CN-1107476-A | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-08-30 | — | — | CN | disclosed |